Development and Structural Analysis of Antibody Therapeutics for Filoviruses

The filoviruses, including ebolaviruses and marburgviruses, are among the world’s deadliest pathogens. As the only surface-exposed protein on mature virions, their glycoprotein GP is the focus of current therapeutic monoclonal antibody discovery efforts. With recent technological developments, poten...

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Bibliographic Details
Main Authors: Xiaoying Yu, Erica Ollmann Saphire
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/11/3/374