Ex vivo and In vitro antiplasmodial activities of approved drugs predicted to have antimalarial activities using chemogenomics and drug repositioning approach

Ex vivo and In vitro antiplasmodial activities of approved drugs predicted to have antimalarial activities using chemogenomics and drug repositioning approach

High malaria mortality coupled with increased emergence of resistant multi-drug resistant strains of Plasmodium parasite, warrants the development of new and effective antimalarial drugs. However, drug design and discovery are costly and time-consuming with many active antimalarial compounds failing...

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Bibliographic Details
Main Authors: Douglas O. Ochora, Reagan M. Mogire, Rael J. Masai, Redemptah A. Yeda, Edwin W. Mwakio, Joseph G. Amwoma, Dancan M. Wakoli, Abiy Yenesew, Hoseah M. Akala
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Antiplasmodial
Chemogenomics
Drug reportioning
Irinotecan
Epirubicin
Ex vivo
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023060711

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http://www.sciencedirect.com/science/article/pii/S2405844023060711

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