Protective role of human beta-defensin-2 and cathelicidin in high risk close household contacts of pulmonary tuberculosis

Host-defense peptides (HDPs) such as human beta-defensin-2 (hBD-2) and cathelicidin (LL37) are essential components of innate immune response against tuberculosis (TB) infection, which could also be assessed for diagnostic potential in spectrum of TB infection. We assessed mRNA and circulating level...

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Main Authors: Sudhasini Panda, Shah Faisal, Diravya M Seelan, Manisha Dagar, Lokesh Mandlecha, Vidushi Varshney, Mridul Sharma, Kalpana Luthra, Neeraj Kumar Gupta, Archana Singh
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Clinical Immunology Communications
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772613423000057