NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8+ T cells for tumor promotion
Activation of the inflammatory transcription factor NF-κB in tumor-associated macrophages (TAMs) is assumed to contribute to tumor promotion. However, whether and how NF-κB drives the antitumor macrophages to become pro-tumorigenic have not been determined in any cancer type yet. Similarly, how TAMs...
Main Authors: | Liwen Li, Lei Han, Fan Sun, Jingjiao Zhou, Kim C. Ohaegbulam, Xudong Tang, Xingxing Zang, Kris A. Steinbrecher, Zhaoxia Qu, Gutian Xiao |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-06-01
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Series: | OncoImmunology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/2162402X.2018.1435250 |
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