Quantitative nuclear histomorphometry predicts oncotype DX risk categories for early stage ER+ breast cancer

Abstract Background Gene-expression companion diagnostic tests, such as the Oncotype DX test, assess the risk of early stage Estrogen receptor (ER) positive (+) breast cancers, and guide clinicians in the decision of whether or not to use chemotherapy. However, these tests are typically expensive, t...

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Bibliographic Details
Main Authors: Jon Whitney, German Corredor, Andrew Janowczyk, Shridar Ganesan, Scott Doyle, John Tomaszewski, Michael Feldman, Hannah Gilmore, Anant Madabhushi
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-4448-9