AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

Abstract Autophagy is essential in physiological and pathological processes, however, the role of autophagy in cutaneous wound healing and the underlying molecular mechanism remain elusive. We hypothesized that autophagy plays an important role in regulating wound healing. Here, we show that enhance...

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Bibliographic Details
Main Authors: Yuanyuan Guo, Cai Lin, Peng Xu, Shan Wu, Xiujun Fu, Weidong Xia, Min Yao
Format: Article
Language:English
Published: Nature Portfolio 2016-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/srep36416