Airway and parenchymal strains during bronchoconstriction in the precision cut lung slice

The precision-cut lung slice (PCLS) is a powerful tool for studying airway reactivity, but biomechanical measurements to date have largely focused on changes in airway caliber. Here we describe an image processing tool that reveals the associated spatio-temporal changes in airway and parenchymal str...

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Bibliographic Details
Main Authors: Jonathan E Hiorns, Cecile M Bidan, Oliver E. Jensen, Reinoud Gosens, Jeffrey J Fredberg, Loes E.M. Kistemaker, Jim P Butler, Ramaswamy Krishnan, Bindi S Brook
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00309/full