Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation

Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation

Abstract Background Bone defects in the maxillofacial region restrict the integrity of dental function, posing challenges in clinical treatment. Bone tissue engineering (BTE) with stem cell implants is an effective method. Nanobiomaterials can effectively enhance the resistance of implanted stem cel...

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Bibliographic Details
Main Authors: Na An, Xiaoyuan Yan, Qiujing Qiu, Zeying Zhang, Xiyue Zhang, Bowen Zheng, Zhenjin Zhao, Jiajie Guo, Yi Liu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Nanobiotechnology
Subjects:
Graphene oxide quantum dots
Periodontal ligament stem cells
Periodontal bone defect
Bone regeneration
Mitochondrial dynamics
Online Access:https://doi.org/10.1186/s12951-024-02422-7

Internet

https://doi.org/10.1186/s12951-024-02422-7

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