Mannose-doped metal-organic frameworks induce tumor cell pyroptosis via the PERK pathway

Mannose-doped metal-organic frameworks induce tumor cell pyroptosis via the PERK pathway

Abstract Background The implementation of pyroptosis exhibits significant potential as a tactic to enhance tumor immune microenvironments. Previous applications of pyroptosis inducers have encountered various limitations, such as the development of drug resistance, manifestation of toxic side effect...

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Bibliographic Details
Main Authors: Nianqiang Jin, Binhang Wang, Xinyao Liu, Chengcheng Yin, Xing Li, Zilin Wang, Xi Chen, Yunling Liu, Wenhuan Bu, Hongchen Sun
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Immunotherapy
ER stress
GSDMD
Pyroptosis
Anti-tumor
Online Access:https://doi.org/10.1186/s12951-023-02175-9

Internet

https://doi.org/10.1186/s12951-023-02175-9

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