Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells.

Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells.

Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection with the ancestral viral isolate. Howe...

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Bibliographic Details
Main Authors: Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C Karawita, Georgina McCallum, Lauren E Steele, Ayaho Yamamoto, Larisa I Labzin, Tejasri Yarlagadda, Alexander A Khromykh, Xiaohui Wang, Julian D J Sng, Claudia J Stocks, Yao Xia, Tobias R Kollmann, David Martino, Merja Joensuu, Frédéric A Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C Bowen, Anthony Kicic, Peter D Sly, Kirsten M Spann, Kirsty R Short
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001728

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https://doi.org/10.1371/journal.pbio.3001728

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