PTEN inhibitor bisperoxovanadium protects against noise-induced hearing loss

PTEN inhibitor bisperoxovanadium protects against noise-induced hearing loss

Studies have shown that phosphatase and tensin homolog deleted on chromosome ten (PTEN) participates in the regulation of cochlear hair cell survival. Bisperoxovanadium protects against neurodegeneration by inhibiting PTEN expression. However, whether bisperoxovanadium can protect against noise-indu...

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Bibliographic Details
Main Authors: Bei Fan, Fei Lu, Wei-Jia Du, Jun Chen, Xiao-Gang An, Ren-Feng Wang, Wei Li, Yong-Li Song, Ding-Jun Zha, Fu-Quan Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
acoustic trauma; akt; oxidative stress; bisperoxovanadium; cochlear hair cells loss; inner hair cell ribbons loss; noise exposure; permanent threshold shift; phosphatase and tensin homologue deleted on chromosome ten; phosphatidylinositol 3 kinase; sipten
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=7;spage=1601;epage=1606;aulast=Fan

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=7;spage=1601;epage=1606;aulast=Fan

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