Harmine Has Nephroprotective Effect Against Methotrexate-Induced Injury in Mice via Inhibition of Oxidative Stress
Background and objectives: Despite clinical use, the efficacy of methotrexate is often limited by some adverse effects, mainly nephrotoxicity. The most common mechanism of methotrexate-induced kidney damages is oxidative stress. Harmine as a plant-derived compound has antioxidant and anti-inflammato...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Iranian Society of Pharmacognosy
2021-10-01
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| Series: | Research Journal of Pharmacognosy |
| Subjects: | |
| Online Access: | http://www.rjpharmacognosy.ir/article_134773_e85014419f9007348a017dc9b4282bb1.pdf |