Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells

Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells

Abstract Background Zinc finger and scan domain containing 18 (ZSCAN18) belongs to the zinc finger transcription factor superfamily, which consists of hundreds of members that play critical roles in all steps of tumorigenesis. Methods This study aims to investigate the roles of ZSCAN18 in gastric ca...

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Bibliographic Details
Main Authors: Bin Li, Baoqing Ren, Gang Ma, Fenglin Cai, Pengliang Wang, Yi Zeng, Yong Liu, Li Zhang, Yang Yang, Han Liang, Rupeng Zhang, Jingyu Deng
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Clinical Epigenetics
Subjects:
Gastric cancer
ZSCAN18
Methylation
Carcinogenesis
Autophagy
Online Access:https://doi.org/10.1186/s13148-023-01425-9

Internet

https://doi.org/10.1186/s13148-023-01425-9

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