Inter-assay variability of next-generation sequencing-based gene panels

Inter-assay variability of next-generation sequencing-based gene panels

Abstract Background Tumor heterogeneity has been known to cause inter-assay discordance among next-generation sequencing (NGS) results. However, whether preclinical factors such as sample type, sample quality and analytical features of gene panel can affect the concordance between two different assa...

Full description

Bibliographic Details
Main Authors: Pham Nguyen Quy, Keita Fukuyama, Masashi Kanai, Tadayuki Kou, Tomohiro Kondo, Masahiro Yoshioka, Junichi Matsubara, Tomohiro Sakuma, Sachiko Minamiguchi, Shigemi Matsumoto, Manabu Muto
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Medical Genomics
Subjects:
Next-generation sequencing
Comprehensive genomic profiling
Clinical sequencing
Gene panel test
Allele frequency
Online Access:https://doi.org/10.1186/s12920-022-01230-y

Internet

https://doi.org/10.1186/s12920-022-01230-y

Similar Items