Characterization of mTOR Activity and Metabolic Profile in Pediatric Rhabdomyosarcoma

Characterization of mTOR Activity and Metabolic Profile in Pediatric Rhabdomyosarcoma

mTOR activation has been observed in rhabdomyosarcoma (RMS); however, mTOR complex (mTORC) 1 inhibition has had limited success thus far. mTOR activation alters the metabolic pathways, which is linked to survival and metastasis. These pathways have not been thoroughly analyzed in RMSs. We performed...

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Bibliographic Details
Main Authors: Luca Felkai, Ildikó Krencz, Dorottya Judit Kiss, Noémi Nagy, Gábor Petővári, Titanilla Dankó, Tamás Micsík, András Khoor, Tamás Tornóczky, Zoltán Sápi, Anna Sebestyén, Monika Csóka
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
mTOR
metabolism
rhabdomyosarcoma
pediatric
Online Access:https://www.mdpi.com/2072-6694/12/7/1947

Internet

https://www.mdpi.com/2072-6694/12/7/1947

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