Multiple functional neurosteroid binding sites on GABAA receptors.

Multiple functional neurosteroid binding sites on GABAA receptors.

Neurosteroids are endogenous modulators of neuronal excitability and nervous system development and are being developed as anesthetic agents and treatments for psychiatric diseases. While gamma amino-butyric acid Type A (GABAA) receptors are the primary molecular targets of neurosteroid action, the...

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Bibliographic Details
Main Authors: Zi-Wei Chen, John R Bracamontes, Melissa M Budelier, Allison L Germann, Daniel J Shin, Krishnan Kathiresan, Ming-Xing Qian, Brad Manion, Wayland W L Cheng, David E Reichert, Gustav Akk, Douglas F Covey, Alex S Evers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000157

Internet

https://doi.org/10.1371/journal.pbio.3000157

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