Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

During cortical development, the identity of major classes of long-distance projection neurons is established by the expression of molecular determinants, which become gradually restricted and mutually exclusive. However, the mechanisms by which projection neurons acquire their final properties duri...

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Bibliographic Details
Main Authors: Kawssar Harb, Elia Magrinelli, Céline S Nicolas, Nikita Lukianets, Laura Frangeul, Mariel Pietri, Tao Sun, Guillaume Sandoz, Franck Grammont, Denis Jabaudon, Michèle Studer, Christian Alfano
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-01-01
Series:eLife
Subjects:
cerebral cortex
layer V projection neurons
epigenetic mechanism
postnatal differentiation
Lmo4
Ctip2/Satb2 coexpression
Online Access:https://elifesciences.org/articles/09531

Internet

https://elifesciences.org/articles/09531

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