8-Hydroxy-2’-Deoxyguanosine and 8-Nitroguanine Production and Detection in Blood Serum of Breast Cancer Patients in Response to Postoperative Complementary External Ionizing Irradiation of Normal Tissues

It is widely known that ionizing irradiation is strongly linked to the production of reactive oxygen (ROS) and nitrative species (RNS) through which DNA damage products like 8-hydroxy-2-deoxyguanosine (8-OHdG) and 8-nitroguanine (8-NG) are generated, respectively. In the present study, we aimed to i...

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Bibliographic Details
Main Authors: Kosmas E. Verigos, Sofia Sagredou, Kyriakos Orfanakos, Panayiotis Dalezis, Dimitrios T. Trafalis
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325820982172