Betaine eliminates CFA-induced depressive-like behaviour in mice may be through inhibition of microglia and astrocyte activation and polarization

Betaine eliminates CFA-induced depressive-like behaviour in mice may be through inhibition of microglia and astrocyte activation and polarization

Chronic pain can induce not only nociceptive but also depressive emotions. A previous study demonstrated that betaine, a commonly used nutrient supplement, has an anti-nociceptive effect, but whether betaine can alleviate chronic pain-induced depressive emotion is elusive. Our current study found th...

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Bibliographic Details
Main Authors: Yue Liang, Ling Chen, Yanmei Huang, Lihua Xie, Xueqin Liu, Wenyan Zhou, Wenyu Cao, Zuyao Chen, Xiaolin Zhong
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Brain Research Bulletin
Subjects:
Betaine
Microglia polarization
Astrocyte polarization
Pain-related depressive-like behaviour
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023002885

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http://www.sciencedirect.com/science/article/pii/S0361923023002885

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