CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction

CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction

Background/AimsChemokines are known to play critical roles mediating inflammation in many pathophysiological processes. The aim of this study was to investigate the role of chemokine receptor CCR4 and its ligands CCL17 and CCL22 in human morbid obesity.MethodsCirculating levels of CCL17 and CCL22 we...

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Bibliographic Details
Main Authors: Luisa Hueso, Patrice Marques, Brenda Morant, Herminia Gonzalez-Navarro, Joaquin Ortega, José T. Real, María J Sanz, Laura Piqueras
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Endocrinology
Subjects:
obesity
adipose tissue
chemokines
inflammation
endothelium
CCL22
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1154158/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1154158/full

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