Identification of polyphenols that repair the ultraviolet-B-induced DNA damage via SIRT1-dependent XPC/XPA activation
Ultraviolet (UV)-B is an established etiological cause of skin damage. SIRT1, a mammalian SIR2 homolog localized in the nucleus and cytosol, plays a protective role in UVB-induced DNA damage. In this study, we established a method of screening foods and food ingredients, which augment the SIRT1 prom...
Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Elsevier
2019-03-01
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Colecção: | Journal of Functional Foods |
Assuntos: | |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1756464619300179 |