A motif-independent metric for DNA sequence specificity

<p>Abstract</p> <p>Background</p> <p>Genome-wide mapping of protein-DNA interactions has been widely used to investigate biological functions of the genome. An important question is to what extent such interactions are regulated at the DNA sequence level. However, curre...

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Bibliographic Details
Main Authors: Pinello Luca, Lo Bosco Giosuè, Hanlon Bret, Yuan Guo-Cheng
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/408