Pencilbeam irradiation technique for whole brain radiotherapy: technical and biological challenges in a small animal model.

We have conducted the first in-vivo experiments in pencilbeam irradiation, a new synchrotron radiation technique based on the principle of microbeam irradiation, a concept of spatially fractionated high-dose irradiation. In an animal model of adult C57 BL/6J mice we have determined technical and phy...

Full description

Bibliographic Details
Main Authors: Elisabeth Schültke, Michael Trippel, Elke Bräuer-Krisch, Michel Renier, Stefan Bartzsch, Herwig Requardt, Máté D Döbrössy, Guido Nikkhah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3557252?pdf=render