Control of translation elongation in health and disease

Control of translation elongation in health and disease

Regulation of protein synthesis makes a major contribution to post-transcriptional control pathways. During disease, or under stress, cells initiate processes to reprogramme protein synthesis and thus orchestrate the appropriate cellular response. Recent data show that the elongation stage of protei...

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Bibliographic Details
Main Authors: John R. P. Knight, Gavin Garland, Tuija Pöyry, Emma Mead, Nikola Vlahov, Aristeidis Sfakianos, Stefano Grosso, Fabio De-Lima-Hedayioglu, Giovanna R. Mallucci, Tobias von der Haar, C. Mark Smales, Owen J. Sansom, Anne E. Willis
Format: Article
Language:English
Published: The Company of Biologists 2020-03-01
Series:Disease Models & Mechanisms
Subjects:
elongation control
protein synthesis
mrna translation control
Online Access:http://dmm.biologists.org/content/13/3/dmm043208

Internet

http://dmm.biologists.org/content/13/3/dmm043208

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