Detection of Somatic Mutations with ddPCR from Liquid Biopsy of Colorectal Cancer Patients

Liquid biopsy and cell-free DNA (cfDNA) show great promise in cancer diagnostics. In this study, we designed a custom droplet digital PCR (ddPCR) assay for the quantification and quality control of cfDNA isolated from serum. The assay was validated on a group of locally advanced colorectal cancer (C...

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Bibliographic Details
Main Authors: Uršula Prosenc Zmrzljak, Rok Košir, Zoran Krivokapić, Dragica Radojković, Aleksandra Nikolić
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/2/289