Formulation and characterization of chitosan nanoparticles to enhance transdermal delivery of cinnarizine.

Cinnarizine (CN) is an antihistaminic drug that is commonly used for the treatment of chronic conditions for the reduction of cerebral blood flow such as vertigo. However, CN is poorly water soluble with erratic absorption and low bioavailability. Chitosan is a biodegradable natural polymer with app...

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Bibliographic Details
Main Authors: Omar A Hamid, Fadia Y Albazzaz, Rasha K Dhahir
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2023-09-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/88226-formulation-and-characterization-of-chitosan-nanoparticles-to-enhance-transdermal-delivery-of-cinnarizine