A putative mitochondrial iron transporter MrsA in Aspergillus fumigatus plays important roles in azole-, oxidative stress responses and virulence

A putative mitochondrial iron transporter MrsA in Aspergillus fumigatus plays important roles in azole-, oxidative stress responses and virulence

Iron is an essential nutrient and enzyme co-factor required for a wide range of cellular processes, especially for the function of mitochondria. For the opportunistic fungal pathogen Aspergillus fumigatus, the ability to obtain iron is required for growth and virulence during the infection process....

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Bibliographic Details
Main Authors: Nanbiao eLong, Xiaoling eXu, Hui eQian, Shizhu eZhang, Ling eLu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Microbiology
Subjects:
Aspergillus fumigatus
iron homeostasis
ROS
Oxidative stresses
histidine residues
mitochondrial iron transporter
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00716/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00716/full

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