Nestin(+) tissue-resident multipotent stem cells contribute to tumor progression by differentiating into pericytes and smooth muscle cells resulting in blood vessel remodeling
Tumor vessels with resistance to anti-angiogenic therapy are characterized by the normalization of the vascular structures through integration of mature pericytes and smooth muscle cells (SMC) into the vessel wall, a process termed vessel stabilization. Unfortunately, stabilization-associated vascul...
Main Authors: | Diana eKlein, Nicole eMeissner, Veronika eKleff, Holger eJastrow, Masahiro eYamaguchi, Süleyman eErgün, Verena eJendrossek |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-06-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00169/full |
Similar Items
-
Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial–mesenchymal transition in lung endothelial cells
by: Wakako Daido, et al.
Published: (2023-09-01) -
Nestin Expression Is Associated with Relapses in Head and Neck Lesions
by: Mario Pérez-Sayáns, et al.
Published: (2021-03-01) -
Nestin-Expressing Cells in the Lung: The Bad and the Good Parts
by: Gilberto Jaramillo-Rangel, et al.
Published: (2021-12-01) -
Nestin Modulates Airway Smooth Muscle Cell Migration by Affecting Spatial Rearrangement of Vimentin Network and Focal Adhesion Assembly
by: Ruping Wang, et al.
Published: (2022-09-01) -
Emerging biomarker in carcinogenesis. Focus on Nestin
by: Katarzyna Nowogrodzka, et al.
Published: (2022-12-01)