Male reproductive phenotype alterations in heterozygous β-globin gene knockout thalassemia (BKO) mice as a model for β-thalassemia patients

Male reproductive phenotype alterations in heterozygous β-globin gene knockout thalassemia (BKO) mice as a model for β-thalassemia patients

Abstract Heterozygous β-globin gene knockout thalassemia (BKO) mice derived from C57BL/6 wild-type (WT) mice have phenotypic of β-thalassemia (BT) and have been widely used for studying this disease except reproductive disorders. The present study determined whether male BKO mice recapitulate reprod...

詳細記述

書誌詳細
主要な著者: Suparada Aiemongkot, Sukanya Ruschadaariyachat, Chinarat Changsangfa, Khanita Nuamsee, Kittikun Viwatpinyo, Pornthip Chaichompoo, Saovaros Svasti, Kakanang Buranaamnuay
フォーマット: 論文
言語:English
出版事項: Nature Portfolio 2025-02-01
シリーズ:Scientific Reports
主題:
β-thalassemia
Hypogonadism
Iron overload
Mouse
Testicular histology
Sperm characteristics
オンライン･アクセス:https://doi.org/10.1038/s41598-025-87619-y

インターネット

https://doi.org/10.1038/s41598-025-87619-y

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