Male reproductive phenotype alterations in heterozygous β-globin gene knockout thalassemia (BKO) mice as a model for β-thalassemia patients

Male reproductive phenotype alterations in heterozygous β-globin gene knockout thalassemia (BKO) mice as a model for β-thalassemia patients

Abstract Heterozygous β-globin gene knockout thalassemia (BKO) mice derived from C57BL/6 wild-type (WT) mice have phenotypic of β-thalassemia (BT) and have been widely used for studying this disease except reproductive disorders. The present study determined whether male BKO mice recapitulate reprod...

Повний опис

Бібліографічні деталі
Автори: Suparada Aiemongkot, Sukanya Ruschadaariyachat, Chinarat Changsangfa, Khanita Nuamsee, Kittikun Viwatpinyo, Pornthip Chaichompoo, Saovaros Svasti, Kakanang Buranaamnuay
Формат: Стаття
Мова:English
Опубліковано: Nature Portfolio 2025-02-01
Серія:Scientific Reports
Предмети:
β-thalassemia
Hypogonadism
Iron overload
Mouse
Testicular histology
Sperm characteristics
Онлайн доступ:https://doi.org/10.1038/s41598-025-87619-y

Інтернет

https://doi.org/10.1038/s41598-025-87619-y

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