Modeling nervous system tumors with human stem cells and organoids

Abstract Nervous system cancers are the 10th leading cause of death worldwide, many of which are difficult to diagnose and exhibit varying degrees of treatment resistance. The limitations of existing cancer models, such as patient-derived xenograft (PDX) models and genetically engineered mouse (GEM)...

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Bibliographic Details
Main Authors: Jie Duan, Yuan Wang
Format: Article
Language:English
Published: SpringerOpen 2023-03-01
Series:Cell Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s13619-022-00150-7