The Evolution of Regulatory Elements in the Emerging Promoter-Variant Strains of HIV-1 Subtype C

The Evolution of Regulatory Elements in the Emerging Promoter-Variant Strains of HIV-1 Subtype C

In a multicentric, observational, investigator-blinded, and longitudinal clinical study of 764 ART-naïve subjects, we identified nine different promoter variant strains of HIV-1 subtype C (HIV-1C) emerging in the Indian population, with some of these variants being reported for the first time. Unlik...

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Main Authors: Disha Bhange, Nityanand Prasad, Swati Singh, Harshit Kumar Prajapati, Shesh Prakash Maurya, Bindu Parachalil Gopalan, Sowmya Nadig, Devidas Chaturbhuj, Boobalan Jayaseelan, Thongadi Ramesh Dinesha, Syed Fazil Ahamed, Navneet Singh, Anangi Brahmaiah, Kavita Mehta, Yuvrajsinh Gohil, Pachamuthu Balakrishnan, Bimal Kumar Das, Mary Dias, Raman Gangakhedkar, Sanjay Mehendale, Ramesh S Paranjape, Shanmugam Saravanan, Anita Shet, Sunil Suhas Solomon, Madhuri Thakar, Udaykumar Ranga
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Microbiology
Subjects:
HIV-1
subtype C
evolution
sequence duplication
latency
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.779472/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.779472/full

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