Targeting Fibronectin to Overcome Remyelination Failure in Multiple Sclerosis: The Need for Brain- and Lesion-Targeted Drug Delivery

Targeting Fibronectin to Overcome Remyelination Failure in Multiple Sclerosis: The Need for Brain- and Lesion-Targeted Drug Delivery

Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease with unknown etiology that can be characterized by the presence of demyelinated lesions. Prevailing treatment protocols in MS rely on the modulation of the inflammatory process but do not impact disease progression. Remyeli...

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Bibliographic Details
Main Authors: Pauline E. M. van Schaik, Inge S. Zuhorn, Wia Baron
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
blood–brain barrier
extracellular matrix
fibronectin
liposomes
multiple sclerosis
nanomedicine
Online Access:https://www.mdpi.com/1422-0067/23/15/8418

Internet

https://www.mdpi.com/1422-0067/23/15/8418

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