Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity

Background Current immunotherapies including checkpoint blockade therapy have limited success rates in certain types of cancers. Identification of alternative checkpoint molecules for the development of effective strategies for tumor immunotherapy is urgently needed. Immunoglobulin-like transcript 4...

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Bibliographic Details
Main Authors: Xia Liu, Lan Huang, Aiqin Gao, Wenli Lin, Jingnan Wang, Shuyun Wang, Fusheng Si, Yangjing Zhao, Yuping Sun, Guangyong Peng
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/3/e001536.full