Dynamic microtubules promote synaptic NMDA receptor-dependent spine enlargement.

Most excitatory synaptic terminals in the brain impinge on dendritic spines. We and others have recently shown that dynamic microtubules (MTs) enter spines from the dendritic shaft. However, a direct role for MTs in long-lasting spine plasticity has yet to be demonstrated and it remains unclear whet...

Full description

Bibliographic Details
Main Authors: Elliott B Merriam, Derek C Lumbard, Chris Viesselmann, Jason Ballweg, Matthew Stevenson, Lauren Pietila, Xindao Hu, Erik W Dent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3214068?pdf=render