Dynamic microtubules promote synaptic NMDA receptor-dependent spine enlargement.
Most excitatory synaptic terminals in the brain impinge on dendritic spines. We and others have recently shown that dynamic microtubules (MTs) enter spines from the dendritic shaft. However, a direct role for MTs in long-lasting spine plasticity has yet to be demonstrated and it remains unclear whet...
Main Authors: | Elliott B Merriam, Derek C Lumbard, Chris Viesselmann, Jason Ballweg, Matthew Stevenson, Lauren Pietila, Xindao Hu, Erik W Dent |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3214068?pdf=render |
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