Haplotype-resolved assembly of auto-polyploid genomes via combining Hi-C and gametic data

Abstract Haplotype-resolved genome assembly plays a crucial role in understanding allele-specific functions. However, obtaining haplotype-resolved assembly for auto-polyploid genomes remains challenging. Existing methods can be classified into reference-based phasing, assembly-based phasing, and gam...

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Bibliographic Details
Main Authors: Xiaohui Zhang, Dongxi Li, Weihua Pan
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-58623-5