Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS

Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS

Osteoarthritis (OA) is one of the most common chronic musculoskeletal disorder worldwide, representing a major source of disability, pain and socioeconomic burden. Yet the effective pharmaceutical treatments applied in the clinical works are merely symptomatic management with uncertainty around thei...

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Bibliographic Details
Main Authors: Changjian Lin, Lujie Ge, Luping Tang, Yuzhe He, Safwat Adel Abdo Moqbel, Kai Xu, Diana Ma, Xing Zhou, Jisheng Ran, Lidong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
osteoarthritis
nitidine chloride
ROS
senescence
NLRP3 inflammasome
MAPK
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.919940/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.919940/full

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