Nox2-dependent neuroinflammation in an EAE model of multiple sclerosis

Multiple sclerosis (MS) is an inflammatory disease of the CNS, characterized by demyelination, focal inflammatory infiltrates and axonal damage. Oxidative stress has been linked to MS pathology. Previous studies have suggested the involvement of NADPH oxidase 2 (Nox2), an enzyme that catalyzes the r...

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Bibliographic Details
Main Authors: Ravelli Katherine G., Santos Graziella D., dos Santos Nilton B., Munhoz Carolina D., Azzi-Nogueira Deborah, Campos Ana Carolina, Pagano Rosana L., Britto Luiz R., Hernandes Marina S.
Format: Article
Language:English
Published: De Gruyter 2019-03-01
Series:Translational Neuroscience
Subjects:
Online Access:https://doi.org/10.1515/tnsci-2019-0001