3-[5-(1<i>H</i>-Indol-3-ylmethylene)-4-oxo-2-thioxothiazolidin-3-yl]-propionic Acid as a Potential Polypharmacological Agent

3-[5-(1<i>H</i>-Indol-3-ylmethylene)-4-oxo-2-thioxothiazolidin-3-yl]-propionic Acid as a Potential Polypharmacological Agent

Searching for new types of biological activities among preliminarily identified hit compounds is a key challenge in modern medicinal chemistry. In our study, a previously studied 3-[5-(1<i>H</i>-indol-3-ylmethylene)-4-oxo-2-thioxothiazolidin-3-yl]-propionic acid (Les-6614) was screened f...

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Bibliographic Details
Main Authors: Yulian Konechnyi, Andrii Lozynskyi, Iryna Ivasechko, Tetiana Dumych, Solomiya Paryzhak, Oksana Hrushka, Ulyana Partyka, Iryna Pasichnyuk, Dmytro Khylyuk, Roman Lesyk
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Scientia Pharmaceutica
Subjects:
2-thioxo-4-thiazolidinones
antimicrobial activity
guinea pigs
inflammation
toxicity
molecular docking
Online Access:https://www.mdpi.com/2218-0532/91/1/13

Internet

https://www.mdpi.com/2218-0532/91/1/13

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