Rapid identification of carbapenem-resistant Klebsiella pneumoniae based on matrix-assisted laser desorption ionization time-of-flight mass spectrometry and an artificial neural network model

Rapid identification of carbapenem-resistant Klebsiella pneumoniae based on matrix-assisted laser desorption ionization time-of-flight mass spectrometry and an artificial neural network model

Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a clinically critical pathogen that causes severe infection. Due to improper antibiotic administration, the prevalence of CRKP infection has been increasing considerably. In recent years, the utilization of matrix-assisted lase...

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Bibliographic Details
Main Authors: Yu-Ming Zhang, Mei-Fen Tsao, Ching-Yu Chang, Kuan-Ting Lin, Joseph Jordan Keller, Hsiu-Chen Lin
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Biomedical Science
Subjects:
Carbapenem-resistant Klebsiella pneumoniae
MALDI-TOF MS
Machine learning
Artificial neural network
Antimicrobial resistance
Feature selection
Online Access:https://doi.org/10.1186/s12929-023-00918-2

Internet

https://doi.org/10.1186/s12929-023-00918-2

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