2-AG-loaded and bone marrow-targeted PCL nanoparticles as nanoplatforms for hematopoietic cell line mobilization

2-AG-loaded and bone marrow-targeted PCL nanoparticles as nanoplatforms for hematopoietic cell line mobilization

Abstract Background The use of mobilizing agents for hematopoietic stem cell (HSC) transplantation is insufficient for an increasing number of patients. We previously reported lipid made endocannabinoid (eCB) ligands act on the human bone marrow (hBM) HSC migration in vitro, lacking long term stabil...

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Bibliographic Details
Main Authors: Sevil Köse, Cem Varan, Selin Önen, Emirhan Nemutlu, Erem Bilensoy, Petek Korkusuz
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Stem Cell Research & Therapy
Subjects:
Cannabinoid
Endocannabinoid
Hematopoietic stem cell
Transplantation
Bone marrow
Mobilization
Online Access:https://doi.org/10.1186/s13287-024-03902-1

Internet

https://doi.org/10.1186/s13287-024-03902-1

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