Preparation of Self-Assembled, Curcumin-Loaded Nano-Micelles Using Quarternized Chitosan–Vanillin Imine (QCS-Vani Imine) Conjugate and Evaluation of Synergistic Anticancer Effect with Cisplatin

Preparation of Self-Assembled, Curcumin-Loaded Nano-Micelles Using Quarternized Chitosan–Vanillin Imine (QCS-Vani Imine) Conjugate and Evaluation of Synergistic Anticancer Effect with Cisplatin

Nano-micelles are self-assembling colloidal dispersions applied to enhance the anticancer efficacy of chemotherapeutic agents. In this study, the conjugate of quarternized chitosan and vanillin imine (QCS-Vani imine) was synthesized using the reaction of a Schiff base characterized by proton-NMR (&l...

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Bibliographic Details
Main Authors: Sasikarn Sripetthong, Sirinporn Nalinbenjapun, Abdul Basit, Suvimol Surassmo, Warayuth Sajomsang, Chitchamai Ovatlarnporn
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Journal of Functional Biomaterials
Subjects:
nano-micelles
quarternized chitosan–vanillin conjugate
curcumin
cisplatin
lung cancer
cytotoxicity evaluation
Online Access:https://www.mdpi.com/2079-4983/14/10/525

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https://www.mdpi.com/2079-4983/14/10/525

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