Rebamipide does not interfere with the antitumor effect of radiotherapy or chemotherapy in human oral tumor-bearing nude mice

Rebamipide does not interfere with the antitumor effect of radiotherapy or chemotherapy in human oral tumor-bearing nude mice

Recent studies have shown that rebamipide, which suppresses reactive oxygen species, prevents chemoradiotherapy-induced oral mucositis in patients with head and neck cancers. However, anticancer action of radiotherapy and chemotherapy is believed to be partially associated with generation of reactiv...

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Bibliographic Details
Main Authors: Masafumi Shibamori, Masayuki Sato, Naoya Uematsu, Takako Nakashima, Asuka Sato, Yoshiya Yamamura, Hiroyuki Sasabe, Ken Umehara, Kazushi Sakurai
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Rebamipide
HSC-2 tumor-bearing nude mice
Radiotherapy
Chemotherapy
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315001486

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http://www.sciencedirect.com/science/article/pii/S1347861315001486

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