A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks

A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks

A live attenuated duck Tembusu virus (TMUV) vaccine FX2010-180P (180P) was successfully utilized to prevent TMUV infections in ducks in China. Compared with wild-type TMUV, 180P was highly attenuated and lost transmissibility in ducks. However, the mechanism of the attenuation of 180P remains poorly...

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Bibliographic Details
Main Authors: Dawei Yan, Binbin Wang, Ying Shi, Xintao Ni, Xiaogang Wu, Xuesong Li, Xingpo Liu, Haiwang Wang, Xin Su, Qiaoyang Teng, Jianmei Yang, Qinfang Liu, Zejun Li
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
Tembusu virus
envelope protein
attenuation
tissue tropism
transmissibility
Online Access:https://www.mdpi.com/1999-4915/14/3/447

Internet

https://www.mdpi.com/1999-4915/14/3/447

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