SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation

Abstract Reissner’s fiber (RF) is an extracellular polymer comprising the large monomeric protein SCO-spondin (SSPO) secreted by the subcommissural organ (SCO) that extends through cerebrospinal fluid (CSF)-filled ventricles into the central canal of the spinal cord. In zebrafish, RF and CSF-contact...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Huixin Xu, Guillaume P. Dugué, Yasmine Cantaut-Belarif, François-Xavier Lejeune, Suhasini Gupta, Claire Wyart, Maria K. Lehtinen
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: BMC 2023-12-01
Цуврал:Fluids and Barriers of the CNS
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1186/s12987-023-00491-8