H3K27me3 Immunohistochemical Loss Predicts Lower Response to Neo-Adjuvant Chemo-Radiotherapy in Rectal Carcinoma

H3K27me3 Immunohistochemical Loss Predicts Lower Response to Neo-Adjuvant Chemo-Radiotherapy in Rectal Carcinoma

A watch-and-wait approach was suggested to avoid the possible complications related to surgery in patients with rectal carcinoma showing clinical complete response after neoadjuvant chemo-radiotherapy (CRT). Since clinical response may not correlate with pathological response, markers with higher ac...

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Bibliographic Details
Main Authors: Serena Ammendola, Nicolò Caldonazzi, Paola Chiara Rizzo, Giulia Turri, Corrado Pedrazzani, Valeria Barresi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
rectal carcinoma
neoadjuvant chemo-radiotherapy
H3K27me3
poorly differentiated clusters
tumor budding
Online Access:https://www.mdpi.com/2227-9059/10/8/2042

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https://www.mdpi.com/2227-9059/10/8/2042

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