Specific β-Turns Precede PPIIL Structures Binding to Allele-Specific HLA-DRβ1* PBRs in Fully-Protective Malaria Vaccine Components

Specific β-Turns Precede PPIIL Structures Binding to Allele-Specific HLA-DRβ1* PBRs in Fully-Protective Malaria Vaccine Components

The 3D structural analysis of 62 peptides derived from highly pathogenic Plasmodium falciparum malaria parasite proteins involved in host cell invasion led to finding a striking association between particular β-turn types located in the N-terminal peripheral flanking residue region (preceding the po...

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Bibliographic Details
Main Authors: Adriana Bermudez, Martha P. Alba, Magnolia Vanegas, Manuel A. Patarroyo, Manuel E. Patarroyo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Chemistry
Subjects:
malaria-vaccine
β-turns
structure-function
IMPIPS
LLPI
PPIIL
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2018.00106/full

Internet

http://journal.frontiersin.org/article/10.3389/fchem.2018.00106/full

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