Excitotoxic degeneration of hypothalamic orexin neurons in slice culture
Several lines of evidence indicate that narcolepsy, a sleep disorder, results from the loss of hypothalamic orexin (hypocretin)-containing neurons, but the mechanisms responsible for selective elimination of this neuronal population are unknown. Using organotypic rat hypothalamic slice cultures, we...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2004-02-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996103001906 |