Investigating regulatory patterns of NLRP3 Inflammasome features and association with immune microenvironment in Crohn’s disease

Investigating regulatory patterns of NLRP3 Inflammasome features and association with immune microenvironment in Crohn’s disease

IntroductionCrohn’s disease is characterized of dysregulated inflammatory and immune reactions. The role of the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome in Crohn’s disease remains largely unknown.MethodsThe microarray-based transcriptomic data and corresponding clinic...

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Bibliographic Details
Main Authors: Huihuan Wu, Ruijie Zeng, Xinqi Qiu, Kequan Chen, Zewei Zhuo, Kehang Guo, Yawen Xiang, Qi Yang, Rui Jiang, Felix W. Leung, Qizhou Lian, Weihong Sha, Hao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Crohn’s disease
NLRP3 inflammasome
immune landscape
drug
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1096587/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1096587/full

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