SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney.

COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that captures all clinical symptoms of COVID-19 as well as long-haulers disease is needed. We investigated the host responses ass...

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Bibliographic Details
Main Authors: Magen Ellen Francis, Una Goncin, Andrea Kroeker, Cynthia Swan, Robyn Ralph, Yao Lu, Athema Louise Etzioni, Darryl Falzarano, Volker Gerdts, Steven Machtaler, Jason Kindrachuk, Alyson Ann Kelvin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009705